Senior Scientist, Discovery Chemistry - Spring House, PA (Job Number: 0502181218)
Description:
Janssen Research & Development, a Johnson & Johnson Company is recruiting
for a Senior Scientist in Computational Chemistry located at Spring
House, PA.
The Discovery Sciences organization within Janssen R&D is continuing to
build key scientific expertise in screening, pharmacology and chemistry
to partner closely with therapeutic area scientists to develop
groundbreaking new medicines in the areas of Oncology, Immunology,
Neuroscience, Cardiovascular, and Infectious Diseases. We are seeking
excellent drug discovery scientists to join the team to bring their
expertise to exciting efforts in novel areas of drug discovery.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, what
matters most is helping people live full and stabilized lives. We
focus on treating, curing and preventing some of the most devastating
and complex diseases of our time. We strive for partnership, and that
has led to numerous breakthroughs. This includes medical miracles that
have changed lives, to the simple consumer products that make every
single day a little better. Our over 125,000 employees in 60 countries
stand united in a common mission: To help people everywhere live longer,
healthier, happier lives. Growing on a diverse company culture, c
elebrating the uniqueness of our employees and committed to diversity.
Proud to be an equal opportunity employer.
As a Senior Scientist, you will apply computational methods, including
structure-based drug design, homology modeling, QSAR, ligand/receptor
docking, high-throughput virtual screening (HTVS), molecular dynamics,
quantum methods and diversity/similarity analysis and machine
learning/artificial intelligence (ML/AI) in the design of individual
molecules and libraries to advance various drug discovery projects.
You will participate in multi-disciplinary teams including chemists,
biologists, and structural biologists providing key expertise in the use
and interpretation of structural data related to drug targets and their
ligands/inhibitors. You will be responsible for:
*Execution of sophisticated experiments using advanced computational
techniques on UNIX-based computer workstations.
*Clear communication of the results of computational experiments and
interpretations of structure to team members facilitating the discovery
of new drugs is expected.
*Development of novel computational methods to address key drug discovery
questions.Qualifications
*A minimum of a PhD in Computational Science or related discipline is
required.
*A minimum of 3 years' experience in the application of computational
chemistry tools to drug discovery is required.
*Familiarity with one or more standard computational chemistry packages
(Maestro/Schrodinger, MOE/Chemical Computing Group, OpenEye tools) is
required.
*Ability to script work flows and implement new algorithms is preferred.
*Experience working with multi-disciplinary teams is required.
*Excellent writing and verbal skills are required.
*Experience with high-throughput virtual screening (HTVS), and/or
machine learning/artificial intelligence (ML/AI) is preferred.
*This position is located at our company site in Spring House, PA.
Johnson & Johnson is an Affirmative Action and Equal Opportunity
Employer. All qualified applicants will receive consideration for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, age, national origin, or protected
veteran status and will not be discriminated against on the basis of
disability.Primary Location:
North America-United States-Pennsylvania-Spring House
Organization:
Janssen Research & Development, LLC. (6084)
Job Function:
Chemistry
Apply Here: http://www.Click2Apply.net/48fn2b9g6gjbksdd
PI111377328
Apply Online: http://www.Click2Apply.net/48fn2b9g6gjbksdd
